Neurology · 1985 · 530 citations · 0 references
Life SciencesBiophysicsPhysiologyMagnetic Resonance BiophysicsNeurochemistryNeurophysiologyCerebral Cortex PhysiologyCerebral PhysiologyMagnetic Resonance SpectroscopyPh AnalysisPka DeterminationIntracellular Ph HomeostasisIntracellular Ph RegulationPh Measurement In Body FluidsPhosphorus-31 Nuclear Magnetic Resonance
We determined cerebral intracellular pH in living rabbits and rats under physiologic conditions, using phosphorus NMR spectroscopy and new titration curves thought to be appropriate for brain. Mean values for the two species were, respectively, 7.14 +/- 0.04 (SD) and 7.13 +/- 0.03. These are toward the alkaline end of the range of values obtained by other methods, as values reported by other NMR workers also tend to be.