Concepedia

Antibodies Against Tumor Necrosis Factor (TNF) Induce T-Cell Apoptosis in Patients With Inflammatory Bowel Diseases via TNF Receptor 2 and Intestinal CD14+ Macrophages

Raja Atreya, Michael Zimmer, Brigitte Bartsch, Maximilian J. Waldner, Imke Atreya, Helmut Neumann, Kai Hildner, Arthur Hoffman, Andreas D. Rink, Tilman T. Rau,

Gastroenterology · 2011 · 252 citations · 33 references

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33

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

Klaus Pfeffer, T. Matsuyama, Thomas M. Kündig et al. · Cell · 1993 · 1.7K citations

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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

, , +17

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)

Hendrik M. van Dullemen, Sander J. H. van Deventer, Daan W. Hommes et al. · Gastroenterology · 1995 · 1.1K citations

, , +9

Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial

William J. Sandborn, S. B. Hanauer, Seymour Katz et al. · Gastroenterology · 2001 · 911 citations · Full text

, , +13

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn’s disease

Jan M. H. van den Brande, Henri Braat, Gijs R. van den Brink et al. · Gastroenterology · 2003 · 725 citations · Full text

, , +16