Concepedia

5′-Aminocarbonyl Phosphonates as New Zidovudine Depot Forms: Antiviral Properties, Intracellular Transformations, and Pharmacokinetic Parameters

Anastasia L. Khandazhinskaya, Dmitry V. Yanvarev, Maxim V. Jasko, Alexander V. Shipitsin, Vsevolod A. Khalizev, Yuriy S. Skoblov, Elena A. Shirokova, Marina K. Kukhanova

Drug Metabolism and Disposition · 2008 · 19 citations · 5 references

DOI

Concepts

References

5

Prodrugs and soft drugs.

Andrzej Stańczak, A. Colomar Ferrá · PubMed · 2007 · 36 citations

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Antiviral Activity and Resistance Profile of Phosphazid - A Novel Prodrug of AZT

John Machado, Horacio Salomón, Maureen Oliveira et al. · Nucleosides and Nucleotides · 1999 · 32 citations

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Uncharged AZT and D4T Derivatives of Phosphonoformic and Phosphonoacetic Acids as Anti-HIV Pronucleosides

Elena A. Shirokova, Maxim V. Jasko, Anastasia L. Khandazhinskaya et al. · Journal of Medicinal Chemistry · 2004 · 31 citations

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Multidose Pharmacokinetics of Ritonavir and Zidovudine in Human Immunodeficiency Virus-Infected Patients

Allen Cato, Jiang Qian, Ann Hsu et al. · Antimicrobial Agents and Chemotherapy · 1998 · 26 citations · Full text

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Intracellular metabolism and pharmacokinetics of 5′-hydrogenphosphonate of 3′-azido-2′,3′-dideoxythymidine, a prodrug of 3′-azido-2′,3′-dideoxythymidine

Yurii S. Skoblov, Inna L. Karpenko, Elena A. Shirokova et al. · Antiviral Research · 2004 · 25 citations

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