Relationship between tissue ischemia and venous endothelin-1 during abdominal aortic aneurysm surgery

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations

Medicine, Vascular Pharmacology, Physiology +6

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

Gilberto De Nucci, Ranjeny Thomas, Pedro D’Orléans-Juste et al. · Proceedings of the National Academy of Sciences · 1988 · 1.4K citations · Full text

Endothelium-derived Relaxing Factor, Pulmonary Arterial Hypertension, Pulmonary Circulation +14

Increased plasma endothelin-1 in the early hours of acute myocardial infarction

Duncan J. Stewart, George Kubac, Kevin B. Costello et al. · Journal of the American College of Cardiology · 1991 · 291 citations

Thrombosis, Vascular Disease, Cardiovascular Disease +10

Endothelin is a positive inotropic agent in human and rat heart in, vitro

Christine S. Moravec, Elwood E. Reynolds, R.W. Stewart et al. · Biochemical and Biophysical Research Communications · 1989 · 232 citations

Heart Failure, Cardiovascular Disease, Medicine +9

Evidence for endothelin-1 release from resistance vessels of rats in response to hypoxia

Hiromi Rakugi, Yoshikatsu Tabuchi, Mitsuaki Nakamaru et al. · Biochemical and Biophysical Research Communications · 1990 · 207 citations

Endothelin-1 Release, Medicine, Physiology +8