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Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: Palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides

Cross-coupling ReactionBiosynthesisBioorganic ChemistryE. ColiBiochemistryPurine RibosidesNatural SciencesEngineeringSubstrate ActivityPeptide SynthesisChemical BiologyBiomolecular Engineering