High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling - Concepedia

Concepedia

Publication | Open Access

High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling

DOI Full Paper Access

47

Citations

15

References

2011

Year

Li Liu, Xiao Hu, Guangyu Cai, Yao Lv, Li Zhuo, Junjie Gao, S.-Y. Cui, Zhichun Feng, Bo Fu, Xinming Chen

Nephrology Dialysis Transplantation

Abstract

PTEN/Akt/mTOR signaling stimulated by high concentration of glucose is regulated by Cx43 overexpression, which unveils part of the molecular mechanism of Cx43 in regulating hyperglycemia-induced hypertrophy.

References

	Year	Citations

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