Angewandte Chemie International Edition · 2010 · 583 citations · 26 references
Natural SciencesChemistryCatalysisOrganic ChemistryCross-coupling ReactionsHeterocycle SynthesisOrganic SynthesisScaffold DiversificationAryl Halide CouplingCross-coupling CatalysisNoble Metal CatalysisPalladium CatalystsPalladium-catalyzed Cross-coupling
Building bridges: Palladium-catalyzed cross-coupling reactions of aryl halides and related compounds allow the expeditious and controlled synthesis of important carbon-based scaffolds (see scheme). Their essential role in organic chemistry has resulted in such reactions being recognized by the Nobel Prize for Chemistry 2010.
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