Studying 18 MDa Virus Assemblies with Native Mass Spectrometry

Abstract

Setting records: Native mass spectometry was used to study the assembly of the 18 MDa capsid of bacteriophage HK97. The previous record for the analysis of capsids by this method was around 10 MDa. The results indicate that the efficiency of desolvation is the main priority in improving native MS instrumentation. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.