Science · 2002 · 654 citations · 8 references
MedicineMolecular BiologyMolecular GeneticsCancer GeneticsGene TherapyMolecular OncologyOncogenic VirusesSafety Of Gene TherapyViral Vector-mediated TransgenesisGene Therapy VectorsGenome Editing Via Viral VectorsRetroviral Gene TransferRetroviral TransgenesisRetroviral VectorsStable Gene TransferTransgene ImmunogenicityTransgene Silencing
Somatic gene transfer is a promising therapeutic strategy, but it may also evoke new types of side effects related to genetic damage or transgene activity. Retroviral vectors, the best tool currently available for stable genetic modification, integrate at random positions in the cellular genome. The
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HSV-TK Gene Transfer into Donor Lymphocytes for Control of Allogeneic Graft-Versus-Leukemia
Chiara Bonini, Giuliana Ferrari, Simona Verzeletti et al. · Science · 1997 · 1.2K citations · Full text
Medicine, Hematology, Immunology +7
The uniqueness of being a neurotrophin receptor
Francis S. Lee, Albert H. Kim, Gus Khursigara et al. · Current Opinion in Neurobiology · 2001 · 196 citations