Antimicrobial Agents and Chemotherapy · 2008 · 95 citations · 23 references
GeneticsKlebsiella PneumoniaeBacteriologyMolecular BiologyEscherichia ColiDiverse Community IsolatesEsbl GenesAntibiotic ResistanceBacterial PathogensDrug ResistanceInfection ControlAntimicrobial ResistanceHealth SciencesMolecular MicrobiologyClinical MicrobiologyAntimicrobial Resistance GenePathogenesisMicrobiologyMedicineMicrobial Genetics
bla(CTX-M) genes, particularly bla(CTX-M-15), are the dominant extended-spectrum beta-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of bla(CTX-M-62), encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids.
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