Archives of Ophthalmology · 1969 · 20 citations · 5 references
MedicineDermatologyImmunologyImmunology Of Infectious DiseasesInflammationOcular ImmunologyCorneal ImmunologyCorneal InfectionHerpetic Eye DiseaseImmunopathology Of The EyeInterferon ResponsesInterferon-based TherapyHerpes Simplex Virus KeratoconjunctivitisHerpetic Epithelial KeratitisInfectious KeratoconjunctivitisInterferon-mediated PathologySystemic Administration
Topical or systemic administration of synthetic double-stranded polyinosinic acid:cytidilic acid RNA prevented the establishment of herpetic keratoconjunctivitis in rabbits. The degree of systemic protection was directly related to the serum level of interferon induced.
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Herbert E. Kaufman, Anthony B. Nesburn, E. D. MALONEY · Archives of Ophthalmology · 1962 · 199 citations