Publication | Closed Access
Sequence‐Controlled Multi‐Block Glycopolymers to Inhibit DC‐SIGN‐gp120 Binding
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Citations
32
References
2013
Year
Synthetic MacromoleculeMulti‐block GlycopolymersBiochemistryNatural SciencesMulti-block GlycopolymersGlycobiologyHiv InfectionMolecular BiologyMacromolecular SystemPolysaccharideProtein EngineeringHivChemical BiologyMedicineCarbohydrate-protein InteractionPolymer ChemistryMonodisperse GlycopolymersGlycosylation
Chain of command: Multi-block glycopolymers made of mannose (M, see figure), glucose, and di(ethylene glycol) ethyl ether (D) monomers were synthesized using a technique to control the polymer sequence. These highly monodisperse glycopolymers were then tested for binding and inhibition of DC-SIGN, a protein important for HIV infection. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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