Solvent resistant microfluidic DNA synthesizer

Yanyi Huang, Piero Castrataro, Cheng-Chung Lee‡, Stephen R. Quake

Lab on a Chip · 2006 · 89 citations · 14 references

Concepts

Abstract

We fabricated a microfluidic DNA synthesizer out of perfluoropolyether (PFPE), an elastomer with excellent chemical compatibility which makes it possible to perform organic chemical reactions, and synthesized 20-mer oligonucleotides on chip.

References

14