Concepedia

Spatial and temporal control of drug release through pH and alternating magnetic field induced breakage of Schiff base bonds

Alexander E. Dunn, Douglas Dunn, Alexander Macmillan, Renée Whan, Timothy Stait‐Gardner, William S. Price, May Lim, Cyrille Boyer

Polymer Chemistry · 2014 · 42 citations · 28 references

DOI

Concepts

Abstract

A novel theranostic controlled drug delivery platform that binds the drug to the nanocarrier by utilising Schiff base bonds to achieve high spatial and temporal control over drug release.

References

28

Controlled growth of monodisperse silica spheres in the micron size range

Werner Stöber, Arthur G. Fink, Ernst Bohn · Journal of Colloid and Interface Science · 1968 · 14.3K citations

, , +16

Acid pH in tumors and its potential for therapeutic exploitation.

Ian F. Tannock, Daniela Rotin · PubMed · 1989 · 1.6K citations

, , +16

Challenges and Key Considerations of the Enhanced Permeability and Retention Effect for Nanomedicine Drug Delivery in Oncology

Uma Prabhakar, Hiroshi Maeda, Eva M. Sevick‐Muraca et al. · Cancer Research · 2013 · 1.5K citations

, , +17

Point by Point Comparison of Two Thermosensitive Polymers Exhibiting a Similar LCST:  Is the Age of Poly(NIPAM) Over?

Jean‐François Lutz, Özgür Akdemir, Ann Hoth · Journal of the American Chemical Society · 2006 · 1.2K citations

, , +15

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

Jeffrey S. Hrkach, Daniel D. Von Hoff, Mir Mukkaram Ali et al. · Science Translational Medicine · 2012 · 1.1K citations

, , +17