Autoimmune encephalitis with GABA _B antibodies, thymoma, and GABA _B receptor thymic expression

Abstract

Antibody-mediated autoimmune encephalopathies comprise a group of severe conditions with a varying degree of motor and cognitive symptoms that respond to immunotherapies.1 The associated antibodies are directed against intracellular targets, such as the classic paraneoplastic autoantigens Hu, Yo, Ri, CV2, Ma2/Ta, or the enzyme GAD, or against cell surface antigens such as receptors and ion channels.