Concepedia

Mice Lacking the Orphan G Protein-Coupled Receptor G2A Develop a Late-Onset Autoimmune Syndrome

Lu Q. Le, Janusz H. Kabarowski, Zhigang Weng, Anne B. Satterthwaite, Eric T. Harvill, Eric R. Jensen, Jeff F. Miller, Owen N. Witte

Immunity · 2001 · 214 citations · 37 references

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37

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

Elizabeth Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity · 1995 · 2.9K citations · Full text

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Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor

Hiroyuki Nishimura, Masato Nose, Hiroshi Hiai et al. · Immunity · 1999 · 2.7K citations · Full text

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In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

Steven R. Schwarze, Alan L. Ho, Adamina Vocero-Akbani et al. · Science · 1999 · 2.4K citations

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Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease

Leonid Gorelik, Richard A. Flavell · Immunity · 2000 · 972 citations · Full text

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Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

Kurt Bachmaier, Connie M. Krawczyk, I. Kozieradzki et al. · Nature · 2000 · 668 citations

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