Locus coeruleus lesions potentiate neurotoxic effects of MPTP in dopaminergic neurons of the substantia nigra

Estimation of nuclear population from microtome sections

M. Abercrombie · The Anatomical Record · 1946 · 4.4K citations

Life Sciences, Genetics, Cytogenetics +4

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

Jonathan A. Javitch, Robert J. D’Amato, Stephen M. Strittmatter et al. · Proceedings of the National Academy of Sciences · 1985 · 1.3K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Biochemical pathophysiology of Parkinson's disease.

O Hornykiewicz, Stephen J. Kish · PubMed · 1987 · 852 citations

Life Sciences, Neurology, Neuroscience +12

Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study

Barbara E. Jones, Robert Y. Moore · Brain Research · 1977 · 847 citations

Medicine, Neurobiology, Neuroscience +10

Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia

William Bondareff, Christopher Q. Mountjoy, Martin Roth · Neurology · 1982 · 691 citations

Medicine, Neurology, Neuroscience +17