Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors

The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2′-5′ oligo (A) synthetase/RNase L pathway

Ji-Young Min, Robert M. Krug · Proceedings of the National Academy of Sciences · 2006 · 478 citations · Full text

Life Sciences, Biology, Molecular Biology +17

Synthesis and antiprotozoal activity of some new synthetic substituted quinoxalines

Hui Xu, Julie Desrivot, Christian Bories et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 191 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Biophysical Characterization of the Complex between Double-Stranded RNA and the N-Terminal Domain of the NS1 Protein from Influenza A Virus:  Evidence for a Novel RNA-Binding Mode

Chen-ya Chien, Yujia Xu, Rong Xiao et al. · Biochemistry · 2004 · 123 citations

Life Sciences, Biophysics, Molecular Biology +17

Hydrogen Bonding Makes a Difference in the Rhodium-Catalyzed Enantioselective Hydrogenation Using Monodentate Phosphoramidites

Yan Liu, Christian A. Sandoval, Yoshiki Yamaguchi et al. · Journal of the American Chemical Society · 2006 · 112 citations

Natural Sciences, Chemical Engineering, Chemistry +17

Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors

Frank Rong, Suetying Chow, Shunqi Yan et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 111 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +12