Depletion of Endoplasmic Reticulum Calcium Stores Protects against Hypoxia- and Mitochondrial Inhibitor-Induced Cellular Injury and Death

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations · Full text

Ca2+ Homeostasis, Intracellular Ca2+ Stores, Cytoskeleton +19

Calcium: still center-stage in hypoxic-ischemic neuronal death

Dennis W. Choi · Trends in Neurosciences · 1995 · 908 citations

Neurophysiology, Hypoxia (Medicine), Hypoxic-ischemic Neuronal Death +11

Calpain: new perspectives in molecular diversity and physiological‐pathological involvement

Takaomi C. Saido, Hiroyuki Sorimachi, Koichi Suzuki · The FASEB Journal · 1994 · 668 citations

Cytoskeleton, Cellular Physiology, New Perspectives +18

Inhibition of the sarcoplasmic reticulum Ca2+ transport ATPase by thapsigargin at subnanomolar concentrations

Yutaka Sagara, Giuseppe Inesi · Journal of Biological Chemistry · 1991 · 458 citations · Full text

Chemical Biology, Enzyme Reactivity, Signal Transduction +15