Analysis of Liver Repair Mechanisms in Alagille Syndrome and Biliary Atresia Reveals a Role for Notch Signaling

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

Linheng Li, Ian D. Krantz, Yu Deng et al. · Nature Genetics · 1997 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +9

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

Takaya Oda, Abdel Elkahloun, Brian L. Pike et al. · Nature Genetics · 1997 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +6

Notch signalling regulates stem cell numbers in vitro and in vivo

Andreas Androutsellis‐Theotokis, Ronen R. Leker, Frank Soldner et al. · Nature · 2006 · 955 citations

Life Sciences, Cell Biology, Developmental Biology +12

NOTCH2 Mutations Cause Alagille Syndrome, a Heterogeneous Disorder of the Notch Signaling Pathway

Ryan M. McDaniell, Daniel M. Warthen, Pedro A. Sanchez‐Lara et al. · The American Journal of Human Genetics · 2006 · 743 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers

Tania Roskams, Neil D. Theise, Charles Balabaud et al. · Hepatology · 2004 · 724 citations · Full text

Medicine, Anatomy, Pathology +17