Genetic association of Toll-like-receptor 4 and tumor necrosis factor-α polymorphisms with Plasmodium falciparum blood infection levels

The global distribution of clinical episodes of Plasmodium falciparum malaria

Robert W. Snow, Carlos A. Guerra, Abdisalan M. Noor et al. · Nature · 2005 · 2.7K citations · Full text

Veterinary Medicine, Health Sciences, Infectious Diseases +14

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

Nancy C. Arbour, Eva Lorenz, Brian C. Schutte et al. · Nature Genetics · 2000 · 2K citations

Life Sciences, Genetics, Immunology +10

Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria

William McGuire, Adrian V. S. Hill, Catherine E. M. Allsopp et al. · Nature · 1994 · 1.2K citations

Veterinary Medicine, Genetics, Molecular Genetics +10

Toll-like Receptor 2 (TLR2) and TLR4 Differentially Activate Human Dendritic Cells

Fabio Re, Jack L. Strominger · Journal of Biological Chemistry · 2001 · 689 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9

Peggy Parroche, Fanny N. Lauw, Nadège Goutagny et al. · Proceedings of the National Academy of Sciences · 2007 · 567 citations · Full text

Life Sciences, Immunology, Molecular Biology +16