Proinflammatory Responses Induced by CD40 in Retinal Endothelial and Muller Cells are Inhibited by Blocking CD40-Traf2,3 or CD40-Traf6 Signaling - Concepedia

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Proinflammatory Responses Induced by CD40 in Retinal Endothelial and Muller Cells are Inhibited by Blocking CD40-Traf2,3 or CD40-Traf6 Signaling

DOI Full Paper Access

23

Citations

45

References

2014

Year

J.-A. Portillo, Ida Vanessa Döederlein Schwartz, Simona Zarini, Reena Bapputty, Timothy S. Kern, Rose Gubitosi‐Klug, Robert C. Murphy, M. Cecilia Subauste, Carlos S. Subauste

Investigative Ophthalmology & Visual Science

Abstract

Blockade of a single CD40-TRAF pathway was sufficient to impair ICAM-1, MCP-1, PGE₂, and VEGF upregulation in retinal endothelial and/or Müller cells. Blockade of CD40-TRAF signaling may control retinopathies.

References

	Year	Citations

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