Mutation of macrophage colony stimulating factor (Csf1) causes osteopetrosis in the tl rat

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

Hisahiro Yoshida, Shinichi Hayashi, Takahiro Kunisada et al. · Nature · 1990 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +9

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

Ji Li, Ildiko Sarosi, Xiaoqiang Yan et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

Medicine, Cell Biology, Genetics +17

Vascular Endothelial Growth Factor Can Substitute for Macrophage Colony-Stimulating Factor in the Support of Osteoclastic Bone Resorption

Shumpei Niida, Masato Kaku, Hitoshi Amano et al. · The Journal of Experimental Medicine · 1999 · 445 citations · Full text

Medicine, Molecular Medicine, Bone Metabolism +13

Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts

Tsuyoshi Miyazaki, Hideki Katagiri, Yumi Kanegae et al. · The Journal of Cell Biology · 2000 · 382 citations · Full text

Life Sciences, Cell Biology, Oral Biology +16

Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation

Gerald J. Atkins, David R. Haynes, Sean M. Geary et al. · Bone · 2000 · 80 citations

Medicine, Cell Biology, Immunology +16