Study of the Protective Effects of Dexamethasone on Ileum Mucosa Injury in Rats With Severe Acute Pancreatitis

Abstract

Dexamethasone can reduce the endotoxin level and inflammatory mediators and down-regulate NF-kappaB protein expression of ileum mucosa, and ileum mucosa epithelial cell apoptosis induction was involved as well. The tissue microarrays technique is of advantage in SAP study.