Concepedia

Increased frequency ofATM mutations in breast carcinoma patients with early onset disease and positive family history

Sharon N. Teraoka, Kathleen E. Malone, David R. Doody, Nicola M. Suter, Elaine A. Ostrander, Janet R. Daling, Patrick Concannon

Cancer · 2001 · 112 citations · 49 references

DOI

Abstract

ATM mutations, specifically missense mutations, are more common in breast carcinoma cases selected for first-degree family history and early age at diagnosis.

References

49

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Kinneret Savitsky, Anat Bar‐Shira, Shlomit Gilad et al. · Science · 1995 · 2.8K citations

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Yi Wang, David Cortez, Parvin T. Yazdi et al. · Genes & Development · 2000 · 1.2K citations · Full text

Chromatin, Genome Instability, Brca1-associated Proteins +13

Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks

David Cortez, Yi Wang, Jun Qin et al. · Science · 1999 · 1K citations

Dna Damage, Checkpoint Kinase Atm, Molecular Biology +17

Incidence of Cancer in 161 Families Affected by Ataxia–Telangiectasia

Michael Swift, Daphne Morrell, Ruby B. Massey et al. · New England Journal of Medicine · 1991 · 946 citations · Full text

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

Dae‐Sik Lim, Seong‐Tae Kim, Bo Xu et al. · Nature · 2000 · 776 citations

Cell Cycle, Tumor Suppressor, S-phase Checkpoint Pathway +4