ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21^Cip1

Douglas Woods, David Parry, Holly Cherwinski et al. · Molecular and Cellular Biology · 1997 · 646 citations · Full text

Cell Proliferation, Cell Cycle, Raf Activity +17

Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

Walter Kölch, Gisela Heidecker, Patricia A. Lloyd et al. · Nature · 1991 · 484 citations

Signal Transduction, Signaling Pathway, Cell Regulation +8

Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases

Richard Marais, Yvonne Light, Hugh F. Paterson et al. · Journal of Biological Chemistry · 1997 · 456 citations · Full text

Signal Transduction, Oncogenic Ras, Signaling Pathway +12

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

Clive Mason · The EMBO Journal · 1999 · 453 citations

Signal Transduction, Signaling Pathway, Biochemistry +10

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.

Michael L. Samuels, Michèle Weber, J. Michael Bishop et al. · Molecular and Cellular Biology · 1993 · 344 citations · Full text

Rapid Activation, Kinase Kinase, Gene Fusion +15