Cytogenetics and Cell Genetics · 2008 · 34 citations · 0 references
Life SciencesCell BiologyGeneticsChromatin StructureCytogeneticsHuman GeneticsChromosomal AbnormalitiesChromosomal DisordersChromosome AberrationsChromosome CondensationMitosisStructural Chromosome AbnormalitiesChromosomal End-to-end FusionChromosome FusionsChromosome Rearrangement MechanismsMitotic Chromosome OrganizationRadial Chromosome ArrangementRing Chromosome Formation
Chain and ring chromosome configurations were detected in a small percentage of the lymphocytes of a patient suffering from Thiberge-Weissenbach syndrome. Precise recognition of the chromosomes involved in the rearrangements did not indicate a systematic order of end-to-end fusions. A relationship between these configurations and the chromosome arrangement in the interphase nucleus is possible.