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The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

Konstantinos Evangelou, Jiřina Bártková, Athanassios Kotsinas, Ioannis S. Pateras, Michalis Liontos, Georgia Velimezi, Triantafillos Liloglou, Ioannis P. Trougakos, Claus L. Andersen, Maria Papaioannou,

Cell Death and Differentiation · 2013 · 59 citations · 37 references

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37

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature · 2005 · 2.7K citations

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Vassilis G. Gorgoulis, Leandros-Vassilios Vassiliou, Panagiotis Karakaidos et al. · Nature · 2005 · 2K citations

, , +16

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

Jiřina Bártková, Nousin Rezaei, Michalis Liontos et al. · Nature · 2006 · 2K citations

, , +16

Ulcerative Colitis and Colorectal Cancer

Anders Ekbom, Charles G. Helmick, Matthew M. Zack et al. · New England Journal of Medicine · 1990 · 1.8K citations · Full text

, , +12

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese et al. · Nature · 2006 · 1.8K citations

, , +16