Concepedia
British Journal of Cancer · 1996 · 103 citations · 32 references
Open access
MedicineOncologyPharmacologyCancer PharmacologyChemotherapyNeoplasiaMalignant NeoplasmsTopoisomerase InhibitorsDna Topoisomerase I InhibitionNeuroblastoma BiologyPeripheral Primitive Neuroectodermal TumorTopoisomerase I Inhibitors
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Amplification of N- <i>myc</i> in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
Garrett M. Brodeur, Robert C. Seeger, Manfred Schwab et al. · Science · 1984 · 2.3K citations
Medicine, Molecular Biology, Oncology +11
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
Olivier Delattre, Jessica Zucman‐Rossi, Béatrice Plougastel-Douglas et al. · Nature · 1992 · 1.9K citations
Life Sciences, Genetics, Molecular Genetics +17
Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.
June L. Biedler, Lawrence Helson, Barbara A. Spengler · PubMed · 1973 · 1.3K citations
Medicine, Cell Biology, Oncology +16
Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin.
Y H Hsiang, M G Lihou, Leroy F. Liu · PubMed · 1989 · 1K citations
Life Sciences, Cell Biology, Molecular Biology +17
CPT-11: a new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer.
N Masuda, M. Fukuoka, Y Kusunoki et al. · Journal of Clinical Oncology · 1992 · 452 citations
Medicine, Oncology, Pharmacology +8