Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/− cells

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

Medicine, Cancer Biology, Molecular Genetics +14

CNS stem cells express a new class of intermediate filament protein

Urban Lendahl, Lyle B. Zimmerman, Ronald D.G. McKay · Cell · 1990 · 3.2K citations

Life Sciences, Cell Biology, Neuroscience +16

Tumor spectrum analysis in p53-mutant mice

Tyler Jacks, Lee Ann Remington, Bart O. Williams et al. · Current Biology · 1994 · 2.1K citations

Medicine, Cancer Biology, Oncology +12

Identification and characterization of the tuberous sclerosis gene on chromosome 16

Cell · 1993 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +7

Identification of the Tuberous Sclerosis Gene <i>TSC1</i> on Chromosome 9q34

Marjon van Slegtenhorst, Ronald De Hoogt, Caroline Hermans et al. · Science · 1997 · 1.7K citations

Medicine, Genetics, Molecular Genetics +16