journal of cancer therapeutics and research · 2012 · 24 citations · 18 references
Life SciencesCell BiologyOncologyApoptosisCell SignalingSignal TransductionAngiogenesisAngiogenesis In CancerApoptosis In CancerApoptosis RegulationApoptotic SignalingDeath ReceptorsApoptosis Of Endothelial CellsFas LigandFas Ligand-mediated ApoptosisPigment Epithelium-derived FactorTumor Vasculature TargetingVascular Endothelial Growth FactorVascular Endothelial Growth Factor InhibitorsVascular Endothelial Growth Factor Signaling
Introduction Angiogenesis and Tumor Growth Angiogenesis, is a normal and necessary process during growth and development. It also occurs in the adult during wound healing and the reproductive cycles. However, in most normal adult issues, the vasculature is maintained in a quiescent state by the balanced presence of both pro-angiogenic and anti-angiogenic
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Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
Thomas Boehm, Judah Folkman, Timothy Browder et al. · Nature · 1997 · 1.7K citations
Medicine, Oncology, Pharmacology +16
Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis
David W. Dawson, Olga V. Volpert, Paul Gillis et al. · Science · 1999 · 1.5K citations
Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1
Kristina M. Dameron, Olga V. Volpert, Michael A. Tainsky et al. · Science · 1994 · 1.4K citations
TUMOR DORMANCY IN VIVO BY PREVENTION OF NEOVASCULARIZATION
Michael A. Gimbrone, Stephen B. Leapman, Ramzi S. Cotran et al. · The Journal of Experimental Medicine · 1972 · 900 citations · Full text
Medicine, Cancer Biology, Oncology +17