Concepedia

Genetically Defined Therapy of Inherited Long-QT Syndrome

Steve Compton, Robert L. Lux, Matthew R. Ramsey, Katie R. Strelich, Michael C. Sanguinetti, Larry S. Green, Mark T. Keating, Jay W. Mason

Circulation · 1996 · 314 citations · 35 references

DOI

Abstract

An increase in serum potassium corrects abnormalities of repolarization duration, T-wave morphology, QT/ RR slope, and QT dispersion in patients with chromosome 7-linked LQT.

References

35

An analysis of the time-relations of electrocardiograms

H. C. Bazett · 1920 · 3.8K citations

, , +6

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

, , +10

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

Mark Curran, Igor Splawski, Katherine W. Timothy et al. · Cell · 1995 · 2.3K citations · Full text

, , +9

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

Qing Wang, Jiaxiang Shen, Igor Splawski et al. · Cell · 1995 · 1.7K citations · Full text

, , +6

Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval, and sudden death

A Jervell, F Lange-Nielsen · American Heart Journal · 1957 · 1.6K citations

, , +6