Severe vitamin D deficiency in patients with Type 2 diabetes in north India

Abstract

SUMMARY Aim: In this study, we aimed to determine the prevalence and correlates of vitamin D deficiency in Asian Indians with Type 2 diabetes mellitus (T2DM) living in north India. Materials & methods: A total of 92 patients with T2DM were compared with nondiabetic patients (n = 92) matched for age, gender, BMI, waist circumference and total body fat. Demographic and clinical parameters, anthropometry (i.e., BMI, waist circumference, waist-to-hip ratio, total body fat and trunk fat), fasting blood glucose, glycosylated hemoglobin and concentration (ng/ml) of serum 25-hydroxy vitamin D3 (25(OH)D3) were assessed. Results: The average concentration of serum 25(OH)D3 (ng/ml; mean ± standard deviation) was significantly lower for T2DM patients as compared with nondiabetic patients (11.0 ± 7.5 vs 15.5 ± 9.8, p = 0.00). Severe vitamin D deficiency (%) was significantly more prevalent among T2DM patients than the nondiabetic patients (57.6 vs 33.3, p = 0.001). The average concentration of serum 25(OH)D3 (ng/ml; m...