Concepedia

Tesofensine, a Novel Triple Monoamine Reuptake Inhibitor, Induces Appetite Suppression by Indirect Stimulation of α1 Adrenoceptor and Dopamine D1 Receptor Pathways in the Diet-Induced Obese Rat

Anne Marie Dixen Axel, Jens D. Mikkelsen, Henrik H. Hansen

Neuropsychopharmacology · 2010 · 48 citations · 45 references

Open access

References

45

Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization.

W. Scott Young, M J Kuhar · Proceedings of the National Academy of Sciences · 1980 · 424 citations · Full text

Medicine, Neuroscience, Pharmacology +13

Defense of differfing body weight set points in diet-induced obese and resistant rats

Barry E. Levin, Richard E. Keesey · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1998 · 247 citations

Agriculture, Animal Sciences, Physiology +13

Evidence for defective mesolimbic dopamine exocytosis in obesity‐prone rats

Brenda M. Geiger, Gerald Behr, L. Frank et al. · The FASEB Journal · 2008 · 195 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial

Arne Astrup, Sten Madsbad, Leif Breum et al. · The Lancet · 2008 · 194 citations

Agriculture, Nutrition, Nutritional Sciences +16

Investigation of the mechanisms underlying the hypophagic effects of the 5‐HT and noradrenaline reuptake inhibitor, sibutramine, in the rat

Helen C. Jackson, M. Clair Bearham, Lisa J. Hutchins et al. · British Journal of Pharmacology · 1997 · 158 citations · Full text

Medicine, Nutritional Sciences, Pharmacology +17