Concepedia

A new nucleic acid–based agent inhibits cytotoxic T lymphocyte–mediated immune disorders

Chuang‐Wei Wang, Yi‐Fang Cheng, Nien-Wen Ying, Konan Peck, Yuan-Tsong Chen

Journal of Allergy and Clinical Immunology · 2013 · 63 citations · 35 references

Concepts

Life SciencesImmunologyPharmacologyImmunoregulationImmunotherapyMolecular ImmunologyCell-mediated ImmunityCytotoxic T Lymphocyte ResponsesImmune Checkpoint InhibitorsNucleic Acid Drug DesignT Cell ActivationT Cell BiologyCytotoxic T Lymphocyte FunctionCytotoxic T-lymphocyte Antigen 4 (Ctla-4) PathwayT Cell-mediated CytotoxicityT-cell Immune ResponsesT-cell Mediated ImmunityT-cell Mediated Responses

References

35

Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412

Ganesh Suntharalingam, Meghan Perry, Stephen Ward et al. · New England Journal of Medicine · 2006 · 2.1K citations

Veterinary Medicine, Immunology, Pharmacology +16

A marker for Stevens–Johnson syndrome

Wen‐Hung Chung, Hong‐Shang Hong, Mo‐Song Hsih et al. · Nature · 2004 · 1.7K citations

Life Sciences, Dermatology, Hypersensitivity +3

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

Wen‐Hung Chung, Lieh-Bang Liou, C.C. Chu et al. · Proceedings of the National Academy of Sciences · 2005 · 1.3K citations

Life Sciences, Genetics, Immunology +12

An Antimicrobial Activity of Cytolytic T Cells Mediated by Granulysin

Steffen Stenger, Dennis A. Hanson, Rachel Teitelbaum et al. · Science · 1998 · 1.1K citations

Life Sciences, Immunology, Microbiology +17

Inhibition of Toxic Epidermal Necrolysis by Blockade of CD95 with Human Intravenous Immunoglobulin

I. Viard, Philippe Wehrli, Roberto Bullani et al. · Science · 1998 · 1K citations

Life Sciences, Immunology, Pharmacology +12