A novel and efficient one step synthesis of 2-amino-5-cyano-6-hydroxy-4-aryl pyrimidines and their anti-bacterial activity

100 years of the biginelli dihydropyrimidine synthesis

C. Oliver Kappe · Tetrahedron · 1993 · 1.2K citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Substituted 1,4-dihydropyrimidines. 3. Synthesis of selectively functionalized 2-hetero-1,4-dihydropyrimidines

Karnail S. Atwal, George C. Rovnyak, Brian C. O'Reilly et al. · The Journal of Organic Chemistry · 1989 · 365 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Novel Biginelli-like three-component cyclocondensation reaction: efficient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones

Zong‐Ting Wang, Li‐Wen Xu, Chungu Xia et al. · Tetrahedron Letters · 2004 · 93 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

A Facile and Efficient One‐Pot Synthesis of Dihydropyrimidinones Catalyzed by Magnesium Bromide Under Solvent‐Free Conditions

Hojatollah Salehi, Qingxiang Guo · Synthetic Communications · 2004 · 78 citations

Natural Sciences, Chemistry, Catalysis +4

Triphenylpropylpiperazine Derivatives as New Potent Analgetic Substances

R. Canevari, J. Le Douarec, S. Holstorp et al. · Journal of Medicinal Chemistry · 1972 · 67 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6