Inhibition of cardiac HERG potassium channels by antidepressant maprotiline

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

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A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

Medicine, Cardiology, Molecular Genetics +16

HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

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Natural Sciences, Genetics, Molecular Genetics +17

A structural basis for drug-induced long QT syndrome

John S. Mitcheson, Jun Chen, Monica Lin et al. · Proceedings of the National Academy of Sciences · 2000 · 937 citations

Medicine, Cardiology, Pharmacology +17

QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients

JG Reilly, I. Nicol Ferrier, SJ Jones et al. · The Lancet · 2000 · 606 citations

Medicine, Pharmacology, Psychiatry +15