Role of LPS in the hepatic microvascular dysfunction elicited by cecal ligation and puncture in mice

Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey Lidicker et al. · Critical Care Medicine · 2001 · 8.6K citations

Veterinary Medicine, Infectious Diseases, Internal Medicine +16

Neutrophil emigration in the skin, lungs, and peritoneum: different requirements for CD11/CD18 revealed by CD18-deficient mice.

PubMed · 1997 · 7.1K citations · Full text

Life Sciences, Immunology, Pathology +15

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai et al. · The Journal of Immunology · 1999 · 3.4K citations · Full text

Life Sciences, Genetics, Immunology +15

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Rintaro Shimazu, Sachiko Akashi, Hirotaka Ogata et al. · The Journal of Experimental Medicine · 1999 · 2.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Essential role of MD-2 in LPS responsiveness and TLR4 distribution

Yoshinori Nagai, Sachiko Akashi, Masakazu Nagafuku et al. · Nature Immunology · 2002 · 1K citations

Veterinary Medicine, Pharmacology, Inflammation +2