Septic Arthritis Complicating Rheumatoid Arthritis

Abstract

Septic arthritis occurred in five patients with advanced rheumatoid arthritis who were confined to a wheelchair or who could perform few of the activities of selfcare. Staphylococcus, Streptococcus, Bacteroides, and a mixed infection of Proteus and Escherichia coli were isolated from the hip, wrist, or knee joints. General debility, decubitus ulcers, steroid treatment, and joint manipulation were probable etiologic factors. The diagnosis of complicating sepsis was most frequently suspected because of the presence of disproportionate pain and swelling in a single joint. Two patients died, and three recovered.