Regulation of the Enzymes of the Hydroaromatic Pathway in Acinetobacter calco-aceticus

Abstract

Summary: The synthesis of dehydroquinase, dehydroshikimate dehydrase and the other enzyme of the hydroaromatic pathway, the hydroaromatic dehydrogenase, was product-induced by protocatechuate in Acinetobacter calco-aceticus. The enzymes of the hydroaromatic pathway and those which subsequently break down protocatechuate are subject to a high degree of coordinate control. Two dehydroquinase isoenzymes exist. The isoenzyme induced by protocatechuate is required for growth on quinate but plays no role in the biosynthesis of aromatic compounds.