Structural Determinants of Efficacy for κ Opioid Receptors in the Orvinol Series:  7,7-Spiro Analogues of Buprenorphine

Abstract

ADVERTISEMENT RETURN TO ISSUELetterNEXTStructural Determinants of Efficacy for κ Opioid Receptors in the Orvinol Series: 7,7-Spiro Analogues of BuprenorphineStephen M. Husbands and John W. LewisView Author Information School of Chemistry, Cantock's Close, University of Bristol, Bristol, England Cite this: J. Med. Chem. 2000, 43, 2, 139–141Publication Date (Web):December 28, 1999Publication History Received15 September 1999Published online28 December 1999Published inissue 1 January 2000https://pubs.acs.org/doi/10.1021/jm991165phttps://doi.org/10.1021/jm991165prapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views414Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Agonists,Alkyls,Conformation,Receptors,Redox reactions Get e-Alerts