Publication | Closed Access
A Novel Organometallic Aqua Complex of Technetium for the Labeling of Biomolecules: Synthesis of [<sup>99m</sup>Tc(OH<sub>2</sub>)<sub>3</sub>(CO)<sub>3</sub>]<sup>+</sup> from [<sup>99m</sup>TcO<sub>4</sub>]<sup>-</sup> in Aqueous Solution and Its Reaction with a Bifunctional Ligand
663
Citations
10
References
1998
Year
We present herein the first synthesis of the water and air stable organometallic aqua complex [<sup>99m</sup>Tc(OH<sub>2</sub>)<sub>3</sub>(CO)<sub>3</sub>]<sup>+</sup> directly from [<sup>99m</sup>TcO<sub>4</sub>]<sup>-</sup> in saline under 1 atm of CO. Subsequent substitution of the labile water ligands by a bifunctional ligand attachable to biomolecules enables the introduction of carbonyl complexes in life sciences in general and in nuclear medicine in particular. [...]
| Year | Citations | |
|---|---|---|
Page 1
Page 1