Cultivation of a Novel Type of Common-cold Virus in Organ Cultures

Abstract

Fourfold or eightfold rise.All sera were tested against influenza A, B, and C, para-influenza 1 and 3 by haemagglutination-inhibition test and against these plus para-influenza 2, mumps V and S antigen, respiratory syncytial virus, herpes simplex, adenoviruses, psittacosis, Rickettsia burnetii, Mycoplasma pneumoniae by complement-fixation test. Clinical Features of Colds Produced by B814 VirusThe frequency of some symptoms, clinical signs, and certain other data regarding volunteers who developed colds after inoculation with B814 material are listed in Table V.This shows that the illnesses were slightly more frequent, were more 1468 5 June 1965Common-cold Viruses-Tyrrell and Bynoe * In first passages control fluids were collected from uninoculated cultures har- vested and stored exactly as the test cultures.For later passages the control fluids were passed serially in parallel with the test cultures.t Identical volunteers