A novel and highly efficient synthesis of the aza analogs of tacrine

A 30-Week Randomized Controlled Trial of High-Dose Tacrine in Patients With Alzheimer's Disease

Margaret J. Knapp · JAMA · 1994 · 975 citations

Pharmacy, Pharmacology, Pharmacotherapy +16

Friedländer reaction on 2-amino-3-cyano-4H-pyrans: Synthesis of derivatives of 4H-pyran [2,3-b] quinoline, new tacrine analogues

A. MARTINEZ‐GRAU, JoséL Marco · Bioorganic & Medicinal Chemistry Letters · 1997 · 319 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group

M. J. Knapp · JAMA · 1994 · 167 citations

Pharmacy, Pharmacology, Pharmacotherapy +13

Acetylcholinesterase inhibition by fused dihydroquinazoline compounds

Juan C. Jaén, V. Gregor, Chet Lee et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 55 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Further studies on the cyclization of aromatic azomethines ortho-substituted with a trifluoromethyl group: synthesis of 2,4-di- or 2,3,4-trisubstituted quinolines

Lucjan Strękowski, Steven E. Patterson, Ľubomír Janda et al. · The Journal of Organic Chemistry · 1992 · 52 citations

Natural Sciences, Chemistry, Inorganic Chemistry +8