A novel sustained-release formulation of insulin with dramatic reduction in initial rapid release

Polymers for the sustained release of proteins and other macromolecules

Róbert Langer, Judah Folkman · Nature · 1976 · 1.2K citations

Pharmacy, Materials Science, Pharmaceutics +14

Dose-response characteristics for effects of insulin on production and utilization of glucose in man

R. A. Rizza, Lawrence J. Mandarino, J. E. Gerich · American Journal of Physiology-Endocrinology and Metabolism · 1981 · 706 citations

Medicine, Biochemistry, Endocrinology +9

Encapsulation of Hydrophilic and Lipophilic Drugs in PLGA Nanoparticles by the Nanoprecipitation Method

José Mário Barichello, Mariko Morishita, Kozo Takayama et al. · Drug Development and Industrial Pharmacy · 1999 · 536 citations

Pharmacy, Pharmaceutics, Pharmacology +17

A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid.

Yasuaki Ogawa, Masaki Yamamoto, Hiroaki Okada et al. · Chemical and Pharmaceutical Bulletin · 1988 · 504 citations · Full text

Pharmacy, Bioengineering, Pharmaceutics +16

A month–long effect from a single injection of microencapsulated human growth hormone

Olufunmi L. Johnson, Jeffrey L. Cleland, Hyejung Lee et al. · Nature Medicine · 1996 · 294 citations

Pharmacy, Endocrinology, Pharmaceutics +15