TGF-β and phorbol esters inhibit mitogenesis utilizing parallel protein kinase C-dependent pathways

TGFβ signals through a heteromeric protein kinase receptor complex

Jeffrey L. Wrana, Liliana Attisano, Juan M. Cárcamo et al. · Cell · 1992 · 1.5K citations

Signal Transduction, Molecular Physiology, Signaling Pathway +5

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

Wayne A. Border, Seiya Okuda, Lucia R. Languino et al. · Nature · 1990 · 1K citations

Glomerular Disease, Renal Pathology, Immunology +17

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation.

Toyoshi Inoguchi, Ruggero Battan, Eugene S. Handler et al. · Proceedings of the National Academy of Sciences · 1992 · 738 citations · Full text

Pancreas Transplantation, Insulin Signaling, Oxidative Stress +21

Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.

Gary H. Gibbons, Richard E. Pratt, Victor J. Dzau · Journal of Clinical Investigation · 1992 · 644 citations · Full text

Cell Proliferation, Ang Ii, Cell Growth +17

Disappearance of Ca2+-sensitive, phospholipid-dependent protein kinase activity in phorbol ester-treated 3T3 cells

Angeles Rodrı́guez-Peña, Enrique Rozengurt · Biochemical and Biophysical Research Communications · 1984 · 631 citations

Signal Transduction, Molecular Physiology, Biochemistry +11