HOXA10 expression induced by Abl kinase inhibitors enhanced apoptosis through PI3K pathway in CML cells

Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

Stephen G. O’Brien, François Guilhot, Richard A. Larson et al. · New England Journal of Medicine · 2003 · 3.6K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

Brian Druker, Charles L. Sawyers, Hagop M. Kantarjian et al. · New England Journal of Medicine · 2001 · 2.7K citations · Full text

Medicine, Hematology, Oncology +17

Induction of Chronic Myelogenous Leukemia in Mice by the P210 ^{<i>bcr/abl</i>} Gene of the Philadelphia Chromosome

George Q. Daley, Richard A. Van Etten, David Baltimore · Science · 1990 · 2.2K citations · Full text

Life Sciences, Hematology, Oncology +15

Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor

Neil P. Shah, Chris Tran, Francis Y. Lee et al. · Science · 2004 · 1.8K citations

Medicine, Oncology, Pharmacology +14

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

Emma Shtivelman, Robert Peter Gale, Eli Canaani · Nature · 1985 · 1.6K citations

Medicine, Molecular Biology, Molecular Genetics +11