Isao Hirano

The FOXM1 transcriptional factor promotes the proliferation of leukemia cells through modulation of cell cycle progression in acute myeloid leukemia

Sayaka Nakamura, Isao Hirano, Keiji Okinaka et al. · Carcinogenesis · 2010 · 106 citations · Full text

Medicine, Cancer Biology, Oncology +16

CMC‐544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B‐cell chronic lymphocytic leukaemia and lymphoma

Akihiro Takeshita, Kaori Shinjo, Nozomi Yamakage et al. · British Journal of Haematology · 2009 · 65 citations

Medicine, Oncology, Pharmacology +17

CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells

Akihiro Takeshita, Nozomi Yamakage, Kaori Shinjo et al. · Leukemia · 2009 · 34 citations

Medicine, Immunology, Oncology +10

Down‐regulation of Thanatos‐associated protein 11 by BCR‐ABL promotes CML cell proliferation through c‐Myc expression

Satoki Nakamura, Daisuke Yokota, Lin Tan et al. · International Journal of Cancer · 2011 · 27 citations · Full text

Medicine, Hematology, Oncology +17

Depletion of Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatases 1 and 2 by Bcr-Abl Promotes Chronic Myelogenous Leukemia Cell Proliferation through Continuous Phosphorylation of Akt Isoforms

Isao Hirano, Satoki Nakamura, Daisuke Yokota et al. · Journal of Biological Chemistry · 2009 · 26 citations · Full text

Life Sciences, Molecular Biology, Oncology +15