Thioredoxin-interacting protein (txnip) is a glucocorticoid-regulated primary response gene involved in mediating glucocorticoid-induced apoptosis

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

A H Wyllie · Nature · 1980 · 4.5K citations

Life Sciences, Cell Biology, Molecular Biology +14

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

A H Wyllie, R. G. Morris, Alex Smith et al. · The Journal of Pathology · 1984 · 1.6K citations

Life Sciences, Cell Biology, Molecular Biology +16

DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival

Holger M. Reichardt, Klaus H. Kaestner, Jan Tuckermann et al. · Cell · 1998 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Identification of Thioredoxin-binding Protein-2/Vitamin D3 Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression

Akira Nishiyama, Minoru Matsui, Satoshi Iwata et al. · Journal of Biological Chemistry · 1999 · 731 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +9

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin

Lisa M. Butler, Xianbo Zhou, Weisheng Xu et al. · Proceedings of the National Academy of Sciences · 2002 · 508 citations · Full text

Medicine, Molecular Biology, Oncology +12