Antipyretic analgesics inhibit prostaglandin release from astrocytes and macrophages similarly

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

John R. Vane · Nature New Biology · 1971 · 8.6K citations

Aspirin-like Drugs, Prostaglandin Synthesis, Biochemistry +8

Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

R J Flower, John R. Vane · Nature · 1972 · 778 citations

Biochemistry, Medicine, Neuropharmacology +8

Pharmacological control of prostaglandin and thromboxane release from macrophages

Kay Brune, Markus Glatt, H. Kälin et al. · Nature · 1978 · 186 citations

Inflammation, Thrombosis, Thrombopoiesis +8

Inhibition by anti-inflammatory drugs of prostaglandin production in cultured macrophages

Kay Brune, K. D. Rainsford, Katharina Wagner et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1981 · 124 citations

Inflammation, Cytokine, Anti-inflammatory +9

Analgesics: Neurochemical, behavioral and clinical perspectives

Anthony H. Dickenson · Pain · 1985 · 108 citations

Pain Therapy, Pain Disorders, Acute Pain +23